There are several promising sickle cell disease treatments in development. While most of the damage to a sickle cell patient results from the actual sickling of the cells, there were no ways to measure red blood cell (RBC) sickling tendency. The RR Mechatronics Lorrca ektacytometer equipped with the Lorrca Oxygenscan is now able to directly measure the characterizing deformability (‘sickling’) of RBCs.